Controlled meal frequency without caloric restriction alters peripheral blood mononuclear cell cytokine production
نویسندگان
چکیده
منابع مشابه
Piperine inhibits cytokine production by human peripheral blood mononuclear cells.
Piperine, an amide isolated from Piper species (Piperaceae), has been reported to exhibit central nervous system depression, anti-pyretic and anti-inflammatory activity. Immunomodulatory and anti-tumor activity of piperine has been demonstrated in mouse carcinomas. However, there is little information available concerning the effect of piperine on humans. We evaluated the immunopharmacolog...
متن کاملCaloric Restriction Alters the Metabolic Response to a Mixed-Meal: Results from a Randomized, Controlled Trial
OBJECTIVES To determine if caloric restriction (CR) would cause changes in plasma metabolic intermediates in response to a mixed meal, suggestive of changes in the capacity to adapt fuel oxidation to fuel availability or metabolic flexibility, and to determine how any such changes relate to insulin sensitivity (S(I)). METHODS Forty-six volunteers were randomized to a weight maintenance diet (...
متن کاملA controlled trial of reduced meal frequency without caloric restriction in healthy, normal-weight, middle-aged adults.
BACKGROUND Although consumption of 3 meals/d is the most common pattern of eating in industrialized countries, a scientific rationale for this meal frequency with respect to optimal health is lacking. A diet with less meal frequency can improve the health and extend the lifespan of laboratory animals, but its effect on humans has never been tested. OBJECTIVE A pilot study was conducted to est...
متن کاملCytokine production in cell culture by peripheral blood mononuclear cells from immunocompetent hosts.
The production of interleukin 2 (IL-2) gamma interferon, IL-4, tumor necrosis factor alpha (TNF-alpha), TNF-beta, IL-5, and IL-10 in vitro by peripheral blood mononuclear cells cultured from healthy immunocompetent subjects after mitogen stimulation was determined. The mitogens used were concanavalin A, phytohemagglutinin, pokeweed mitogen, and Staphylococcus aureus Cowen. The results obtained ...
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Most individuals latently infected with Mycobacterium tuberculosis (M.tb) contain the infection by a balance of effector and regulatory immune responses. This balance can be influenced by steroid hormones such as glucocorticoids. The widely used contraceptive medroxyprogesterone acetate (MPA) possesses glucocorticoid activity. We investigated the effect of this hormone on immune responses to BC...
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ژورنال
عنوان ژورنال: Journal of Inflammation
سال: 2011
ISSN: 1476-9255
DOI: 10.1186/1476-9255-8-6